Current Medicinal Chemistry |
Загальні терміни та фрази
3-D structures 3H]DAMGO 3H]ohmefentanyl 4a and 4b acidic groups agonistic activity agonists amisulpride analgesic analgesic activity analog entry antagonistic activities antiemetic antipsychotic arginine residue aromatic ring Bentham Science Publishers benzamide derivatives binding affinity biological activity c/s-A-ohmefentanyl carbon carboxylic acid charged nitrogen N+ Chart CHCH2N cisapride clebopride CO2H compounds contractile activity Current Medicinal Chemistry CysLT1 CysLT1 antagonists CysLT1 receptor antagonists cysteine-glycine dazopride diastereoisomeric pairs Drug Eight Ohmefentanyl EPS side effects fentanyl four c/s-stereoisomers highly potent hydrogen bonding hydroxyl Institute of Materia interaction isomers 4a isothiocyanate leukotriene leukotriene analogues ligand lipophilic lipophilic tail LTC4 LTD4 LTE4 mg/kg mixture molecular molecule morphine mouse hot plate NCOCH2CH3 nemonapride ohmefentanyl ohmefentanyl stereoisomers opioid receptors p-hydroxyl group p-phenethyl peptide pharmacological pharmacophoric pharmacophoric model piperidine positively charged nitrogen propionanilide quinoline receptor antagonists Replacement Shanghai Institute stereoisomers structure/activity studies substituent sulpiride synthesis Table tail flick tetrazole tiapride veralipride Vesnarinone