Bioactive Natural Products Detection, Isolation, and Structural Determination
Bioactive Natural Products covers all the aspects of bioactive natural product research from ethnobotanical investigations to modern, technologically assisted isolation and structural determination of active compounds. An internationally selected group of experts share their knowledge of a wide range of bioactivities and chemical compound classes.
Topics in the chapters describing the modern application of detection, isolation, and structural determination techniques are strongly supported by chapters detailing and reviewing research involving various classes of bioactivity. Research areas include the immunomodulatory, antiviral, cytotoxic, anti-inflammatory, and insect behavior classes of bioactivity.
Extensive referencing throughout the text is helpful to those readers not familiar with this subject and serves as a critical review for more experienced researchers. The book is also excellent for upper division or post-graduate courses.
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Detection and Isolation of Bioactive Natural Products 9
Cryptic Bioactive Natural Products
Strategies for Structural
Determination of ThreeDimensional Structure and Configuration
Determination of the Absolute Configuration of Bioactive Natural
Techniques of Isolation
Insect Behavior Modifiers
Assessment of AntiInflammatory Activity of Natural Products
Biologically Active Terpenoids and Aromatic Compounds
Antiviral Agents from Higher Plants and an Example
Toxicity Testing Using the Brine Shrimp Artemia salina
An Approach to Toxin Isolation
absolute configuration acetate active compounds agents aglycone alkaloids analysis anomeric antibiotics antitumor antiviral antiviral activity aqueous assay assignment atoms bioactive bioassay biologically active C-NMR cancer carbon cell lines Chem chemical shift Chemistry chirality chromatography coherence transfer column concentration correlation cryptoporic acid crystal cytotoxic detection diosgenin drug effect eluted ether experiments fetal Figure flavonoids fraction glucose glycosides H-NMR HETCOR heteronuclear Hostettmann HPLC immunomodulators immunomodulatory inhibition inhibitor insect interactions ions isolation leukocytes Magn magnetic mass spectrometry metabolites methanol method methyl mixture molecular molecule natural products NMR spectroscopy NOEs nuclei observed partitioning peaks Phytochemistry plant extracts polar polysaccharides potential Prod products chemistry protein protons pulse purification residues resonance rhamnose sample saponin 9 saponins screening selective separation sequence sesquiterpene signals silica gel soluble solution solvent species spectra spectrum stereochemistry structure determination sugar sweet technique toxic tumor virus vitro vivo X-ray