Bioprinting: Principles And Applications
At labs around the world, researchers have been experimenting with bioprinting, first just to see whether it was possible to push cells through a printhead without killing them (in most cases it is), and then trying to make cartilage, bone, skin, blood vessels, small bits of liver and other tissues. There are other ways to try to “engineer” tissue — one involves creating a scaffold out of plastics or other materials and adding cells to it. In theory, at least, a bioprinter has advantages in manipulating control of the placement of cells and other components to mimic natural structures.But just as the claims made for 3-D printing technology sometimes exceed the reality, the field of bioprinting has seen its share of hype. The reality is that, although bioprinting researchers have made great strides, there are many formidable obstacles to overcome. Nobody who has any credibility claims they can print organs, or believes in their heart of hearts that that will happen in the next 20 years, but for operations like hip replacement, advance in Bio-printing has made customization of certain body parts possible.This book will start from the concept of Tissue Engineering, covering various approaches in Scaffolds for tissue engineering, Bioprinting techniques and Materials for bioprinting, Cell processing, 3D cell culture techniques, Computational design and simulation, multi-disciplinary approaches in bioprinting and finally cover the applications of bioprinting.
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3D bioprinting 3D cell culture 3D printing 3D tissue acid additive manufacturing adhesion alginate applications architecture bioactive biocompatible biodegradable Biofabrication biological Biomaterials biomechanical biomedical materials research biomimetic bioprinting bioreactor Biotechnology bone tissue engineering C. K. Chua cartilage cartridge cell culture CellJet cellular collagen computational Computer-Aided crosslinking degradation differentiation dispensing droplets drug ejected EnvisionTEC extrusion fibres fluid formation function fused deposition modelling fusion gels human hydrogels imaging implants inkjet printing interactions Journal of biomedical K. F. Leong layer liquid matrix mechanical properties mesenchymal stem cells methods multicellular nozzle organ Organovo peptide perfusion PLGA PLLA polycaprolactone polymer pore porosity porous scaffolds pressure proliferation Rapid Prototyping scaffold design scaffold fabrication Science selective laser sintering shear simulation solvent specific stem cells structure substrate surface synthetic temperature three-dimensional tissue engineering tissue engineering scaffolds tissue scaffolds transplantation unit cells utilised vascular viscosity vitro vivo