Cell Therapy: Stem Cell Transplantation, Gene Therapy, and Cellular Immunotherapy

Передня обкладинка
George Morstyn, William Sheridan
Cambridge University Press, 29 бер. 1996 р. - 617 стор.
Cell therapy is a rapidly developing area, drawing on cell biology, molecular biology, virology, immunology, cell quantitation techniques and biomedical engineering. It has potential in many clinical settings, in the treatment of cancer and other diseases.This volume in the series Cancer: Clinical Science in Practice examines the current state and future prospects of cell therapy, which seems likely to have an even more profound impact on health care than did the production of proteins by recombinant DNA technology. The coverage is broad, including the scientific principles of haematopoietic cell therapy, the technology of cell collection and preparation, current and likely future clinical applications of cell therapy, and the principles and practice of cellular immunotherapy.Up-to-date and authoritative, volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.
 

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Зміст

Effector Cells of Experimental and Clinical Cellular
18
Current and Potential Uses of Defined Cell
47
Flow Cytometric Techniques
75
Principles of Gene Therapy
91
Sources of Hemopoietic Progenitor Cells
113
CHRISTOPHER HOGAN SCOTTI BEARMAN AND ROY B JONES
130
CytokineOnly Approaches to Mobilization
146
Characterization and Isolation of Mobilized
183
Treatment of Solid Tumors with HighDose
312
HighDose Chemotherapy with Cellular Support
337
Allogeneic Marrow Transplantation as Treatment
352
Clinical Gene Therapy
369
Gene Therapy of Enzyme and Immune Deficiencies
386
Cellular Therapy Approaches to the Treatment
414
Adoptive Immunotherapy with T Cells
429
Cellular Adoptive Immunotherapy with Natural
451

Hemopoietic Stem Cell Selection Using Monoclonal
199
Magnetic Approaches to Cell Separation
213
Growth Factors and Ex Vivo Expansion
221
Bioreactors for Expansion
238
Purging of Malignant Cells
250
DoseIntensive Chemotherapy without Hemopoietic
269
Clinical Potential of Hemopoietic GrowthFactor
299
Autologous Tumor Cell Vaccines
475
Neutrophil Transfusions for Treatment of Infections
510
Experimental and Clinical Cellular Immunotherapy
527
Donor Lymphocyte Therapy in BoneMarrow
550
GraftVersusLeukemia Effect in BoneMarrow
568
Index
587
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