The Search for Bioactive Compounds from MicroorganismsSatoshi Omura Springer Science & Business Media, 22 жовт. 1992 р. - 352 стор. Biologically active compounds isolated from microorganisms continue to be vital to the development of new drugs and agricultural chemicals. This book was prepared by current and past members of the laboratory of Dr. Satoshi Omura of the Kitasato Institute in Japan. Dr. Omura and his colleagues have discovered and studied a number of important antibiotics, and in their work they have pioneered new methods for screening microbes for interesting and important compounds. This book presents strategies and methods for identifying novel molecules with several types of biological activity. In addition, the book discusses the identification of microbial compounds of agrochemical importance, presents information on chemical screening methods, and concludes with chapters on microbial strain selection, fermentation technology, and genetic engineering of antibiotic-producing microorganisms. This book will be of great interest to scientists working in the very active and competitive fields of antibiotic and agrochemical discovery. |
Зміст
Antibacterial Agents | 1 |
Antifungal Agents | 30 |
Antiviral Agents | 45 |
Antiparasitic Agents | 63 |
Antitumor Substances | 78 |
Antitumor Agents | 79 |
Cell Differentiation Inducers | 104 |
Enzyme Inhibitors | 116 |
Agrochemicals | 212 |
Fungicides and Antibacterial Agents | 213 |
Herbicides | 224 |
Insecticides Acaricides and Anticoccidial Agents | 237 |
Chemical Screening | 262 |
Chemical Screening | 263 |
Sources Fermentation and Improvement of Producing Microorganisms | 280 |
Selection of Microbial Sources of Bioactive Compounds | 281 |
General Screening of Enzyme Inhibitors | 117 |
New Strategy for Search of Enzyme Inhibitors | 161 |
Pharmacologically Active Substances | 170 |
Immunomodulators | 171 |
Vasoactive Substances | 198 |
Fermentation Processes in Screening for New Bioactive Substances | 303 |
Genetic Engineering of AntibioticProducing Microorganisms | 327 |
337 | |
Інші видання - Показати все
The Search for Bioactive Compounds from Microorganisms Satoshi Omura Обмежений попередній перегляд - 2012 |
The Search for Bioactive Compounds from Microorganisms Satoshi Omura Попередній перегляд недоступний - 2011 |
The Search for Bioactive Compounds from Microorganisms Satoshi Omura Попередній перегляд недоступний - 1992 |
Загальні терміни та фрази
Actinomadura actinomycetes acyl-CoA Agricultural and Biological alkaloid aminopeptidase anthelmintic antibacterial antibiotics produced Antibiotics Tokyo anticoccidial antifungal Antimicrobial antitumor antibiotic antiviral agents Aoyagi assay avermectin bacteria biological activity Biological Chemistry biosynthesis biotics Tokyo buffer Candida Carbapenem cell wall cephalosporins CH₂ CH3 CH3 COOH culture broth cyclosporin detected differentiation discovered diseases drugs effect enzyme inhibitors fatty acid Figure fungal fungi gene glucose growth H₂C Hamada herbicidal Imanaka immunomodulators incubated induced infection inhibition inhibitory activity isolation Iwai Journal of Anti Journal of Antibiotics Kitasato Institute Kohsaka leukemia macrolide metabolites mice microbial metabolites microbial origin microorganisms monobactam mutant Naganawa novel Ōmura penicillin plant plate platelet platelet aggregation potent produced by Streptomyces protein kinase screening method screening system soil ß-lactam antibiotics Staurosporine strain Streptomyces Streptomyces sp structure substances Suzuki synthesis synthetase Takahashi Takeuchi Tanaka target Taxonomy test organism triacsins Umezawa virus vitro vivo Yoshida µg ml-¹ ОН